The prevalence of CA and CP increased gradually with age. Ten-year stroke and CHD risk were determined using the United Kingdom Prospective Diabetes Study (UKPDS) risk engine. CA and CP were detected using ultrasonography. We studied 1584 T2DM patients aged 20 years and older. We aimed to determine the prevalence of CA and CP and their relationship with 10-year risks of stroke and coronary heart disease (CHD) in type 2 diabetes mellitus (T2DM). Ĭarotid atherosclerosis (CA) and carotid plaque (CP) are highly correlated with cardiovascular disease.
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This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The authors declare that there is no conflict of interest regarding the publication of this paper. PFS designed the research and wrote the manuscript.įunding/support: This study received funding from the National Natural Science Foundation of China (81370968, 81670744), the Chinese Society of Endocrinology (13040620447), the Department of Education, Zhejiang Province (Y201328533), the Natural Science Foundation of Zhejiang Province (LY14H160023), and Medical and Health Research Fund of Zhejiang Province (2017KY561). XS, YMZ, HYL, XLJ, XHP, LZS, YXK, and YJW conducted the study. YW and JH conducted the study and wrote the manuscript. China (e-mail: ).Ībbreviations: ARIC = Atherosclerosis Risk in Communities, BMI = body mass index, CA = carotid atherosclerosis, CHD = coronary heart disease, CI = confidence interval, CIMT = carotid intima–media thickness, CP = carotid plaque, CVD = cardiovascular diseases, HbA1c = glycated hemoglobin, HDL-c = high-density lipoprotein cholesterol, LDL-c = low-density lipoprotein cholesterol, NS = no statistical significance, OR = odds ratio, SBP = systolic blood pressure, SD = standard deviation, T2DM = type 2 diabetes mellitus, UKPDS = United Kingdom Prospective Diabetes Study.Īuthorship: PFS will handle the production process if accepted. China.Ĭorrespondence: Peng-Fei Shan, Department of Endocrinology and Metabolism, the Second Affiliated Hospital ZheJiang University College of Medicine, Hangzhou, 88 Jiefang Rd, Zhejiang 310009, P.R. ADepartment of Endocrinology and Metabolism, the Second Affiliated Hospital ZheJiang University College of MedicineīDepartment of Endocrinology and Metabolism, Zhejiang Greentown Cardiovascular HospitalĭDepartment of Clinical Laboratory, the Second Affiliated Hospital ZheJiang University College of Medicine, Hangzhou, Zhejiang, P.R.
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